Canine Spectra 10 Plus Lyme has been shown to be effective for the vaccination of healthy dogs 9 weeks of age or older against canine distemper virus (CDV), infectious canine hepatitis (CAV1), canine adenovirus type 2 (CAV2), canine coronavirus (CCV), canine parainfluenza (CPIV), and canine parvovirus (CPV), Leptospira canicola, Leptospira icterohaemorrhagiae, Leptospira grippotyphosa, Leptospira pomona and Borrelia burgdorferi (Bburg). The duration of immunity for Borrelia burgdorferi is at least 12 months. The duration of immunity for the other antigens has not been established. For more information regarding efficacy and safety data go to productdata.aphis.usda.gov. See packaging for complete product details.